Patients < 35 years with adrenal lesion ≧1cm can also receive AVS if clinically indicated Abbreviations: APA, aldosterone-producing adenomas; ARR, aldosterone-to-renin ratio; AVS, adrenal venous sampling; CT, computed tomography; NP-59- SPECT, I-131-6-beta-iodomethyl-19-norcholesterol single-photon emission computed tomography.